Week 13 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay would pay out 25-1

The Minnesota Vikings will try to pick up their 10th win of the season when they face the New York Jets on Sunday during the Week 13 NFL schedule. Minnesota bounced back from its second loss of the season with a 33-26 win over New England last week. The Jets have split their last four games, picking up a 31-10 win over Chicago their last time out. Minnesota is a three-point favorite in the Week 13 NFL odds at Caesars Sportsbook. Other intriguing Week 13 NFL spreads include Philadelphia (-5.5) vs. Tennessee and Kansas City (-2.5) at Cincinnati. Which Week 13 NFL lines should you target with your Week 13 NFL bets? Before you make any Week 13 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 13 of the 2022 NFL season on an incredible 155-110 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 13. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 13 NFL picks at SportsLine.

Top Week 13 NFL picks

After simulating every game 10,000 times, the model is high on the San Francisco 49ers (-3.5) to cover against the Miami Dolphins. San Francisco is one of the hottest teams in the NFL, riding a four-game winning streak coming into this matchup. The 49ers have won three of those four games by double-digits and have only lost one game since acquiring running back Christian McCaffrey.

McCaffrey and Elijah Mitchell are averaging more than four yards per carry, while 49ers quarterback Jimmy Garoppolo has thrown for more than 2,300 yards and 16 touchdowns. Miami squeaked out road wins at Detroit and Chicago one month ago, but the Dolphins have not faced a legitimate opponent on the road since getting blown out by the Jets in Week 5. San Francisco covers the spread in almost 60% of simulations. See which other NFL parlay picks to make here.

How to make Week 13 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including a pair of underdogs that are projected to win outright. You can only see the model’s NFL Week 13 best bets and parlay at SportsLine

What are the model’s top Week 13 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 13 NFL best bets from a model on a 155-110 run on its top-rated picks, and find out.

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